A UPS airplane crashed near Louisville Muhammad Ali International Airport shortly after takeoff, prompting a shelter-in-place order for residents in the area. According to reports, UPS Flight 2976, an MD-11 freighter with three crew members aboard, was involved in an accident around 5:20 PM ET. UPS confirmed the incident but stated no injuries or casualties had been verified at this time.

The National Transportation Safety Board is overseeing the investigation, with UPS indicating it will provide further details as they become available. The MD-11F, a freight transport aircraft manufactured by McDonnell Douglas and later Boeing, is capable of carrying up to 38,000 gallons of fuel.

Louisville Metro Police confirmed multiple injuries following the crash near the UPS Worldport facility. Authorities described the scene as “active with fire and debris” and urged residents to stay away. A shelter-in-place alert was issued for areas north of the airport to the Ohio River.

Sources indicated an engine issue occurred during takeoff, though no official confirmation has been provided. The FAA and NTSB are investigating the incident, which led to the closure of the airport. A large plume of smoke was reported near the site.